McHale Leah, Tan Xiaoping, Koehl Patrice, Michelmore Richard W
The Genome Center, University of California, Davis, CA 95616, USA.
Genome Biol. 2006;7(4):212. doi: 10.1186/gb-2006-7-4-212. Epub 2006 Apr 26.
The majority of disease resistance genes in plants encode nucleotide-binding site leucine-rich repeat (NBS-LRR) proteins. This large family is encoded by hundreds of diverse genes per genome and can be subdivided into the functionally distinct TIR-domain-containing (TNL) and CC-domain-containing (CNL) subfamilies. Their precise role in recognition is unknown; however, they are thought to monitor the status of plant proteins that are targeted by pathogen effectors.
植物中的大多数抗病基因编码核苷酸结合位点富含亮氨酸重复序列(NBS-LRR)蛋白。这个大家族在每个基因组中由数百个不同的基因编码,并且可以细分为功能上不同的含TIR结构域(TNL)和含CC结构域(CNL)的亚家族。它们在识别中的精确作用尚不清楚;然而,人们认为它们负责监测病原体效应子所靶向的植物蛋白的状态。