不宁腿综合征与多发性神经病。

Restless legs syndrome and polyneuropathy.

作者信息

Gemignani Franco, Brindani Francesca, Negrotti Anna, Vitetta Francesca, Alfieri Sara, Marbini Adriana

机构信息

Department of Neurosciences, Section of Neurology, University of Parma, Parma, Italy.

出版信息

Mov Disord. 2006 Aug;21(8):1254-7. doi: 10.1002/mds.20928.

DOI:10.1002/mds.20928

PMID:16685701

Abstract

Restless legs syndrome (RLS), diagnosed according to the International RLS Study Group criteria, was investigated in 97 consecutive patients with polyneuropathy and found in 29 patients. RLS patients were more often women (22 of 29 vs. 33 of 68; P = 0.015), mainly with sensory neuropathy of small fiber type (15 of 29 vs. 16 of 68; P = 0.009). Changes of sensory action potentials were significantly less severe in RLS patients. In the RLS group, acquired neuropathies, and in particular dysimmune neuropathies, were significantly more frequent (27/29 vs. 46/68; P = 0.009). Thus, RLS is frequent in acquired polyneuropathy of sensory type and mild entity, mainly in women.

摘要

根据国际不宁腿综合征研究组标准诊断的不宁腿综合征（RLS），在97例连续性多神经病患者中进行了调查，发现29例患者患有该综合征。RLS患者女性更为常见（29例中的22例 vs. 68例中的33例；P = 0.015），主要为小纤维型感觉神经病（29例中的15例 vs. 68例中的16例；P = 0.009）。RLS患者感觉动作电位的变化明显较轻。在RLS组中，获得性神经病，尤其是免疫性神经病，明显更为常见（27/29 vs. 46/68；P = 0.009）。因此，RLS在感觉型和轻度的获得性多神经病中很常见，主要见于女性。