Anveden Ingegärd, Wrangsjö Karin, Järvholm Bengt, Meding Birgitta
Occupational and Environmental Health, Centre for Public Health, Stockholm, Sweden.
Contact Dermatitis. 2006 May;54(5):272-7. doi: 10.1111/j.0105-1873.2006.00823.x.
The aim was to study self-reported skin exposure in individuals from the general population with or without hand eczema. In a population-based study in 1996 using postal questionnaires to 3000 individuals, 215 of 2218 (9.7%) reported hand eczema during the past 12 months. 182 (85%) of those with hand eczema and 182 without hand eczema, matched for age and sex, participated in telephone interviews in 1997 regarding exposure to skin irritants at work and in leisure time. No differences were shown in occupational exposure to water, hand washing or chemicals in individuals with or without hand eczema. Women reported more wet exposure than men at work and in leisure time. A correlation was found between occupational wet exposure and wet work at home. Persons in high-risk occupations reported more frequent exposure to skin irritants. However, 53% in high-risk occupations reported exposure to water and detergents for less than half-hour a day and 11% in low-risk occupations for more than half-hour a day. In conclusion, individuals with or without hand eczema seem to have similar exposure to skin irritants. Using job titles as a proxy for exposure gives misclassification, which may result in underestimation of the hand eczema risk.
目的是研究普通人群中患有或未患手部湿疹的个体的自我报告的皮肤暴露情况。在1996年一项基于人群的研究中,通过邮政问卷对3000名个体进行调查,2218名中有215名(9.7%)报告在过去12个月内患有手部湿疹。1997年,182名患有手部湿疹的人和182名年龄和性别匹配的未患手部湿疹的人参与了关于工作和休闲时间接触皮肤刺激物的电话访谈。患有或未患手部湿疹的个体在职业接触水、洗手或接触化学物质方面没有差异。女性报告在工作和休闲时间比男性有更多的湿接触。发现职业湿接触与在家中的湿工作之间存在相关性。高风险职业的人报告更频繁地接触皮肤刺激物。然而,高风险职业中有53%的人报告每天接触水和洗涤剂的时间少于半小时,低风险职业中有11%的人报告每天接触时间超过半小时。总之,患有或未患手部湿疹的个体似乎接触皮肤刺激物的情况相似。用职业头衔作为接触的替代指标会导致错误分类,这可能会低估手部湿疹的风险。