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[鼻腔血管肉瘤:一例报告及文献综述]

[Nasal cavity angiosarcoma: a case report and literature review].

作者信息

Ordoñez-Escalante Karla Gabriela, Mantilla-Morales Alejandra, Gallegos Francisco

机构信息

Servicio de Anatomía Patológica, Hospital de Oncología Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico D. F., Mexico.

出版信息

Gac Med Mex. 2006 Mar-Apr;142(2):155-8.

Abstract

Sarcomas constitute 5% of all of head and neck neoplasms. Angiosarcomas comprise 2% of all soft tissue tumors, 60% appear in skin and soft tissue, 50% in the head and neck and only 4% are present in the upper aerodigestive tract. We report a case of a 52 year old healthy woman with headache, weeping, foreign body sensation in the left nostril and epixtasis. The TAC identified a tumor in the left nostril that invaded the osseous lamina of the skull. The histopathologic diagnosis was angiosarcoma. We carried out a literature review and analysis from 1976 to 2004. Agiosarcomas of the upper aerodigestive tract have a better prognosis and long term survival free of disease than their soft tissue and skin counterparts. Recurrence is strongly correlated with positive resection margins. Complete surgery and radiotherapy are considered the optimal treatment schemes.

摘要

肉瘤占所有头颈部肿瘤的5%。血管肉瘤占所有软组织肿瘤的2%,60%出现在皮肤和软组织中,50%位于头颈部,仅4%存在于上呼吸道消化道。我们报告一例52岁健康女性,有头痛、流涕、左侧鼻孔异物感和鼻出血症状。计算机断层血管造影(TAC)发现左侧鼻孔有一肿瘤,侵犯了颅骨骨板。组织病理学诊断为血管肉瘤。我们对1976年至2004年的文献进行了回顾和分析。上呼吸道消化道血管肉瘤比其软组织和皮肤同类肿瘤预后更好,长期无病生存率更高。复发与手术切缘阳性密切相关。完整手术和放疗被认为是最佳治疗方案。

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