Liner Lisa H, Marcus Carole L
Virtua Voorhees-West Jersey Hospital, Voorhees, New Jersey, USA.
Curr Opin Pediatr. 2006 Jun;18(3):272-6. doi: 10.1097/01.mop.0000193301.63259.84.
The purpose of this review is to summarize the current management of continuous positive airway pressure and noninvasive positive pressure ventilation in children with sleep-disordered breathing.
Although most children with sleep-disordered breathing respond to surgical treatment, the use of continuous positive airway pressure and noninvasive positive pressure ventilation in nonresponders has become common, with hundreds of cases reported in the literature, despite the fact that these devices are not approved by the Food and Drug Administration for use in children weighing under 30 kg. Studies show that continuous positive airway pressure and non-invasive positive pressure ventilation are safe and efficacious. Side-effects are minor, and include nasal symptoms and skin breakdown. Midfacial hypoplasia is an uncommon adverse event. Problems with triggering and cycling of noninvasive positive pressure ventilation remain an issue in small or weak children. As in adults, poor adherence is the major obstacle to successful continuous positive airway pressure or noninvasive positive pressure ventilation use.
Continuous positive airway pressure is a useful second-line treatment for children with sleep-disordered breathing. Strategies to improve adherence are needed. Equipment manufacturers should be encouraged to develop equipment that better meets children's needs.
本综述旨在总结目前对睡眠呼吸障碍儿童持续气道正压通气和无创正压通气的管理。
尽管大多数睡眠呼吸障碍儿童对手术治疗有反应,但对于无反应者使用持续气道正压通气和无创正压通气已变得普遍,文献中报道了数百例病例,尽管这些设备未获得美国食品药品监督管理局批准用于体重低于30公斤的儿童。研究表明,持续气道正压通气和无创正压通气是安全有效的。副作用较小,包括鼻部症状和皮肤破损。面中部发育不全是一种罕见的不良事件。在体型小或体弱的儿童中,无创正压通气的触发和切换问题仍然存在。与成人一样,依从性差是持续气道正压通气或无创正压通气成功使用的主要障碍。
持续气道正压通气是睡眠呼吸障碍儿童有用的二线治疗方法。需要采取提高依从性的策略。应鼓励设备制造商开发更能满足儿童需求的设备。