Schwartz D L, Garden A S
Department of Radiation Oncology, M.D. Anderson Cancer Center, Unit 97, 1515 Holcombe Boulevard, Houston, TX 77030, USA.
Hematol Oncol Clin North Am. 2006 Apr;20(2):259-85. doi: 10.1016/j.hoc.2006.02.001.
The length and quality of head and neck cancer survivorship continues to improve. Radiotherapy has been central to this process through advances in treatment technology, fractionation schemas, radiosensitizing chemotherapy, and surgical technique. The future of head and neck radiotherapy looks brighter still with progress in radiosensitizing biologic therapy, molecular characterization, functional imaging, and rehabilitative strategies fast approaching. Head and neck cancer, a disease once fraught with nihilism and failure, is evolving into a major success story of multidisciplinary solid tumor management. Continued dedication and work on the part of provider and patient alike will be required to make this promise a reality.
头颈癌幸存者的生存期长度和质量持续改善。通过治疗技术、分割方案、放射增敏化疗以及手术技术的进步,放射治疗在这一过程中发挥了核心作用。随着放射增敏生物治疗、分子特征分析、功能成像以及康复策略的快速发展,头颈放射治疗的前景愈发光明。头颈癌,一种曾经充满虚无主义和失败的疾病,正逐渐演变成多学科实体肿瘤管理的一个重大成功案例。医患双方都需要持续奉献和努力,才能让这一愿景成为现实。