南非叶中的植物雌激素。
Phytoestrogens from Aspalathus linearis.
机构信息
School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan.
出版信息
Biol Pharm Bull. 2006 Jun;29(6):1271-4. doi: 10.1248/bpb.29.1271.
PMID:16755032
Abstract
From the leaves of Aspalathus linearis, 24 known compounds and a new one, aspalalinin (25), were isolated. The structures of the compounds were determined mainly based on spectral evidence. The absolute configuration of aspalalinin was presented on the basis of X-ray analysis. Each isolate was assessed for its estrogenic activity by an estrogen ELISA assay. Compounds 12, 15, and 24 showed the estrogenic activity.
摘要
从线性Aspalathus 叶中分离得到 24 种已知化合物和一种新化合物，aspalalinin（25）。化合物的结构主要基于光谱证据确定。aspalalinin 的绝对构型基于 X 射线分析提出。通过雌激素 ELISA 测定，评估了每种分离物的雌激素活性。化合物 12、15 和 24 显示出雌激素活性。
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