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胰头肿块患儿的管理

Management of children with pancreatic head mass.

作者信息

Park Jinyoung, Dunn James C Y, Atkinson James B

机构信息

Department of Pediatric Surgery, School of Medicine, Kyungpook National University, Taegu, Korea.

出版信息

J Pediatr Surg. 2006 Jun;41(6):e1-4. doi: 10.1016/j.jpedsurg.2006.02.029.

Abstract

The management of children with a mass in the head of the pancreas is not well defined. The medical records of 3 children with obstructive jaundice because of a mass in the head of the pancreas over a 4-year period were reviewed retrospectively. Abdominal ultrasonography and computed tomography showed intrahepatic and extrahepatic ductal dilatation and a pancreatic mass. Intraoperative frozen section revealed no evidence of malignancy. These patients were separately managed by pylorus-preserving pancreaticoduodenectomy, cholecystectomy and Roux-en-Y choledochojejunostomy, common duct exploration, and T-tube drainage. The final pathology of the pancreatic head mass in all cases demonstrated chronic pancreatitis. Follow-up at an average of 7 months postoperatively showed no recurrence of obstructive jaundice. Unlike adults with a mass in the head of the pancreas, it is recommended that children with similar presentation should undergo biopsy and biliary diversion rather than resection as the primary therapy. Adults presenting with similar radiologic and clinical features would be treated by a pancreaticoduodenectomy in the absence of histologic evidence of malignancy. This series would suggest histologic conformation should be obtained before radical surgery in children.

摘要

胰腺头部有肿块的儿童的治疗方法尚无明确界定。回顾性分析了4年间3例因胰腺头部肿块导致梗阻性黄疸的儿童的病历。腹部超声和计算机断层扫描显示肝内和肝外胆管扩张以及胰腺肿块。术中冰冻切片未发现恶性证据。这些患者分别接受了保留幽门的胰十二指肠切除术、胆囊切除术和 Roux-en-Y 胆总管空肠吻合术、胆总管探查术和 T 管引流术。所有病例中胰腺头部肿块的最终病理结果均显示为慢性胰腺炎。术后平均7个月的随访显示无梗阻性黄疸复发。与胰腺头部有肿块的成人不同,建议有类似表现的儿童应进行活检和胆道转流术,而不是将切除作为主要治疗方法。在没有恶性组织学证据的情况下,具有类似影像学和临床特征的成人将接受胰十二指肠切除术治疗。该系列研究表明,儿童在进行根治性手术前应获得组织学证实。

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