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[Anomaly in the neurotransmitter amino acids in amyotrophic lateral sclerosis: a therapeutic application].

作者信息

Blin O, Desnuelle C, Guelton C, Aubrespy G, Ardissonne J P, Crevat A, Pouget J, Serratrice G

机构信息

Clinique des Maladies du Système Nerveux et de l'Appareil Locomoteur, Marseille.

出版信息

Rev Neurol (Paris). 1991;147(5):392-4.

PMID:1677212
Abstract

Although the cause of amyotrophic lateral sclerosis remains unknown, the excitatory amino acids may be involved in its pathogenesis. Glutamate level analysis shows a differential distribution of the amino acids. One of the therapeutic methods consists of reinforcing the inhibitory amino acid activity using L-threonine which has been shown to improve some symptoms and signs of ALS.

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