Blin O, Desnuelle C, Guelton C, Aubrespy G, Ardissonne J P, Crevat A, Pouget J, Serratrice G
Clinique des Maladies du Système Nerveux et de l'Appareil Locomoteur, Marseille.
Rev Neurol (Paris). 1991;147(5):392-4.
Although the cause of amyotrophic lateral sclerosis remains unknown, the excitatory amino acids may be involved in its pathogenesis. Glutamate level analysis shows a differential distribution of the amino acids. One of the therapeutic methods consists of reinforcing the inhibitory amino acid activity using L-threonine which has been shown to improve some symptoms and signs of ALS.