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使用IntraLase飞秒激光进行LASIK术后发生脓肿分枝杆菌角膜炎。

Mycobacterium abscessus keratitis after LASIK with IntraLase femtosecond laser.

作者信息

Chung So-Hyang, Roh Mi In, Park Min Soo, Kong Young Tae, Lee Hyung Keun, Kim Eung Kweon

机构信息

Department of Ophthalmology, Institute of Vision Research, Yonsei University College of Medicine, Seoul, Korea.

出版信息

Ophthalmologica. 2006;220(4):277-80. doi: 10.1159/000093084.

Abstract

A healthy 38-year-old woman developed 2 white spots in her left eye 2 weeks after bilateral laser in situ keratomileusis (LASIK) using the IntraLase femtosecond laser. Initial treatment included levofloxacin 0.5% but was unsuccessful. The surgeon irrigated the interface and repositioned the flap due to a worsened lesion. She was referred to us after the keratitis had not improved. The flap was lifted for collection of the specimen and irrigation of the interface. The keratitis was treated with intensive topical clarithromycin 1%, amikacin 1.25% and oral clarithromycin, which improved her clinical condition. She developed a toxic reaction to amikacin 1.25%, which was replaced by moxifloxacin 0.5%. Mycobacterium abscessus was identified. The keratitis resolved over 2 months. Five months after treatment, the patient had a visual acuity of 20/20 with correction. Nontuberculous mycobacteria should be considered as an etiologic agent, even in cases of infectious keratitis after LASIK using the femtosecond laser.

摘要

一名38岁健康女性在使用IntraLase飞秒激光进行双眼准分子原位角膜磨镶术(LASIK)后2周,左眼出现2个白色斑点。初始治疗包括使用0.5%左氧氟沙星,但未成功。由于病变恶化,外科医生冲洗了角膜瓣界面并重新定位了角膜瓣。在角膜炎未改善后,她被转诊至我们这里。掀起角膜瓣以采集标本并冲洗界面。使用1%克拉霉素、1.25%阿米卡星局部强化治疗以及口服克拉霉素治疗角膜炎,改善了她的临床状况。她对1.25%阿米卡星产生了毒性反应,改用0.5%莫西沙星。鉴定出脓肿分枝杆菌。角膜炎在2个月内消退。治疗5个月后,患者矫正视力为20/20。即使在使用飞秒激光的LASIK术后感染性角膜炎病例中,非结核分枝杆菌也应被视为病原体。

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