Ali C Rubina, Fitzgerald C
Department of Assisted Reproduction, St Mary's Hospital, Whitworth Park, Manchester M13 0JH, UK.
Reprod Biomed Online. 2006 Jun;12(6):776-8. doi: 10.1016/s1472-6483(10)61090-5.
Omental pregnancy is an uncommon form of abdominal pregnancy; it has never been previously reported after IVF. A 35-year-old patient underwent IVF for tubal factor infertility. The treatment cycle was uneventful, but 3 weeks following embryo transfer the patient was diagnosed with a right tubal ectopic pregnancy on ultrasound. A laparoscopic salpingectomy was performed and the patient was discharged home. Two weeks later, the patient presented with abdominal pain and rising serum beta-human chorionic gonadotrophin (beta-HCG). A repeat laparoscopy showed omental and peritoneal trophoblastic implants. These were excised laparoscopically and confirmed on histology to be trophoblastic tissue. The HCG returned to < 3 IU/l, 1 week post-operatively. This case emphasizes the importance of intra-operative care during laparoscopic surgery for ectopic pregnancy and the need for post-operative surveillance of serum beta-HCG. An abdominal pregnancy, though rare, has a seven times higher mortality rate than non-abdominal pregnancies. Early diagnosis and treatment can prevent intra-abdominal haemorrhage, as haemorrhagic shock is the commonest cause of mortality from omental pregnancy.
大网膜妊娠是腹内妊娠的一种罕见形式;此前体外受精(IVF)后从未有过相关报道。一名35岁患者因输卵管因素不孕接受了体外受精治疗。治疗周期顺利,但胚胎移植3周后,超声检查诊断该患者为右侧输卵管异位妊娠。遂行腹腔镜输卵管切除术,患者出院回家。两周后,患者出现腹痛,血清β-人绒毛膜促性腺激素(β-HCG)水平升高。再次腹腔镜检查发现大网膜和腹膜有滋养层植入物。通过腹腔镜将其切除,组织学检查证实为滋养层组织。术后1周,HCG降至<3 IU/l。该病例强调了腹腔镜异位妊娠手术中术中护理的重要性以及术后监测血清β-HCG的必要性。腹内妊娠虽然罕见,但其死亡率比非腹内妊娠高7倍。早期诊断和治疗可预防腹腔内出血,因为出血性休克是大网膜妊娠最常见的死亡原因。