Holmfred Anette, Vikerfors Thomas, Berggren Lars, Gupta Anil
Department of Anesthesiology, Orebro University Hospital, Orebro, Sweden.
J Pain Symptom Manage. 2006 Jun;31(6):568-72. doi: 10.1016/j.jpainsymman.2005.11.010.
Intrathecal catheters have been used for many years to treat severe pain resistant to conventional treatment modalities. Previous studies have found a rate of serious infection of 2%-3% using these catheters in home situations. However, many authors used prophylactic antibiotics routinely in this group of patients, which are both costly and associated with a risk of developing antibiotic resistance. We were interested in studying whether improved hygiene during insertion and care of these catheters in the hospice or home environment would reduce the incidence of catheter-related infections. The results show that prophylactic antibiotic is not necessary, but a careful handling of the system with aseptic technique is important. The infections we registered appeared more than 2 weeks after insertion of the catheters. We now use this method routinely when inserting an intrathecal catheter with a subcutaneous port.
鞘内导管已被用于治疗对传统治疗方式耐药的重度疼痛多年。既往研究发现,在家庭环境中使用这些导管时,严重感染率为2%-3%。然而,许多作者在这类患者中常规使用预防性抗生素,这既昂贵又有产生抗生素耐药性的风险。我们感兴趣的是,在临终关怀机构或家庭环境中,改善这些导管插入和护理过程中的卫生状况是否会降低导管相关感染的发生率。结果表明,预防性使用抗生素没有必要,但采用无菌技术仔细操作该系统很重要。我们记录的感染发生在导管插入2周以后。现在,我们在插入带皮下端口的鞘内导管时常规使用这种方法。