Wolterink Joanne Klein, Barkema Gerard T, Panja Debabrata
Institute for Theoretical Physics, Universiteit Utrecht, Minnaertgebouw, Leuvenlaan 4, Postbus 80.195, 3508 TD Utrecht, The Netherlands.
Phys Rev Lett. 2006 May 26;96(20):208301. doi: 10.1103/PhysRevLett.96.208301. Epub 2006 May 25.
We study the translocation process of a polymer in the absence of external fields for various pore diameters b and membrane thickness L. The polymer performs Rouse and reptation dynamics. The mean translocation time (tau(t)) that the polymer needs to escape from a cell and the mean dwell time (tau(d)) that the polymer spends in the pore during the translocation process obey scaling relations in terms of the polymer length N, L, and b/R(g), where R(g) is the radius of gyration for the polymer. We explain these relations using simple arguments based on polymer dynamics and the equilibrium properties of polymers.
我们研究了在不存在外部场的情况下,聚合物在各种孔径(b)和膜厚度(L)条件下的转位过程。聚合物表现出Rouse动力学和蛇行动力学。聚合物从细胞中逸出所需的平均转位时间((\tau(t)))以及在转位过程中聚合物在孔中停留的平均时间((\tau(d))),根据聚合物长度(N)、(L)和(b/R(g))遵循标度关系,其中(R(g))是聚合物的回转半径。我们基于聚合物动力学和聚合物的平衡性质,用简单的论据解释了这些关系。