Hedrick Traci L, Sawyer Robert G, Foley Eugene F, Friel Charles M
Department of Surgery, University of Virginia Health System, Charlottesville, Virginia 22901, USA.
Dis Colon Rectum. 2006 Aug;49(8):1167-76. doi: 10.1007/s10350-006-0602-6.
Anastomotic disruption is an uncommon but morbid complication of colon and rectal surgery. This study was designed to evaluate the use of proximal diversion and surgical drainage as an alternative to anastomotic resection in the operative management of patients with anastomotic complications.
A retrospective chart review was undertaken of all patients on the colon and rectal surgery service at an academic medical center requiring operative intervention for an anastomotic complication between 1998 and 2005. Demographic data, operative management, morbidity, and mortality were collected and analyzed for each patient.
Twenty-seven patients with anastomotic leaks were included in the study. Nineteen patients were managed with proximal diversion and surgical drainage, six patients had resection of their anastomosis and creation of an end colostomy, and two patients were treated by primary reanastomosis. There was 0 percent mortality. Sixty-three percent of the patients treated with proximal diversion had restoration of intestinal continuity vs. 33 percent of the patients who had the anastomosis resected. Of the 13 patients treated with proximal diversion who underwent fluoroscopic evaluation, 92 percent were normal without evidence of persistent leak or stricture.
Based on this retrospective study, proximal diversion without resection of the anastomosis seems to be a safe and effective alternative for the treatment of anastomotic complications. Sepsis is well controlled with limited mortality and there is a high rate of anastomotic salvage. Prospective studies are needed to further delineate the optimal management for this complicated patient population.
吻合口破裂是结肠和直肠手术中一种不常见但严重的并发症。本研究旨在评估近端转流术和手术引流作为吻合口并发症患者手术治疗中吻合口切除替代方法的应用。
对1998年至2005年间在一家学术医疗中心接受结肠和直肠手术治疗且因吻合口并发症需要手术干预的所有患者进行回顾性病历审查。收集并分析每位患者的人口统计学数据、手术治疗情况、发病率和死亡率。
27例吻合口漏患者纳入研究。19例患者采用近端转流术和手术引流治疗,6例患者进行了吻合口切除并造端结肠造口,2例患者接受了一期再次吻合术。死亡率为0%。接受近端转流术治疗的患者中有63%恢复了肠道连续性,而接受吻合口切除的患者中这一比例为33%。在接受近端转流术治疗并接受透视评估的13例患者中,92%情况正常,无持续性漏或狭窄迹象。
基于这项回顾性研究,不切除吻合口的近端转流术似乎是治疗吻合口并发症的一种安全有效的替代方法。脓毒症得到良好控制,死亡率有限,吻合口挽救率高。需要进行前瞻性研究以进一步明确针对这一复杂患者群体的最佳治疗方法。