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年龄和种族能否预测所接受的乳腺癌治疗?一项基于城市人群的横断面研究。乳腺癌治疗:年龄与种族。

Do age and ethnicity predict breast cancer treatment received? A cross-sectional urban population based study. Breast cancer treatment: age and ethnicity.

作者信息

Naeim Arash, Hurria Arti, Leake Barbara, Maly Rose C

机构信息

Division of Hematology-Oncology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095-1687, USA.

出版信息

Crit Rev Oncol Hematol. 2006 Sep;59(3):234-42. doi: 10.1016/j.critrevonc.2006.03.002. Epub 2006 Jul 10.

Abstract

PURPOSE

To evaluate the treatment patterns of women aged 55 years or older with newly diagnosed breast cancer and to examine the association between age and ethnicity/race on treatment selection.

METHODS

A cross-sectional survey between January 1 and June 30, 2001 of 401 women was performed of Hispanic, black and non-Hispanic white women in Los Angeles County, aged 55 years or older with newly diagnosed breast cancer. Regression analysis examined the association between: (a) age and treatment selection and (b) ethnicity/race and treatment selection, adjusting for the effect of possible confounders.

RESULTS

In this study of urban breast cancer patients (64.1% response rate), blacks were less likely to receive hormone (OR=0.36) or chemotherapy therapy (OR=0.50) while older patients were less likely to receive lymph node dissection after lumpectomy (OR=0.48) and chemotherapy (OR=0.22).

CONCLUSION

Although there are racial and age disparities in breast cancer treatment, other factors such as education, income status, insurance plan, functional status, and comorbidity also play an important role.

摘要

目的

评估55岁及以上新诊断乳腺癌女性的治疗模式,并研究年龄与种族在治疗选择上的关联。

方法

于2001年1月1日至6月30日对洛杉矶县401名55岁及以上新诊断乳腺癌的西班牙裔、黑人及非西班牙裔白人女性进行了横断面调查。回归分析研究了以下两者之间的关联:(a)年龄与治疗选择;(b)种族与治疗选择,并对可能的混杂因素的影响进行了调整。

结果

在这项针对城市乳腺癌患者的研究(应答率为64.1%)中,黑人接受激素治疗(比值比=0.36)或化疗的可能性较小(比值比=0.50),而老年患者在保乳术后接受淋巴结清扫(比值比=0.48)和化疗(比值比=0.22)的可能性较小。

结论

尽管乳腺癌治疗存在种族和年龄差异,但教育、收入状况、保险计划、功能状态和合并症等其他因素也起着重要作用。

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