[系统性硬化症中HAQ-DI的意大利语版本]
[HAQ-DI Italian version in systemic sclerosis].
作者信息
La Montagna G, Cuomo G, Chiarolanza I, Ruocco L, Valentini G
机构信息
Dipartimento di Internistica Clinica e Sperimentale F. Magrassi e A. Lanzara, Seconda Università degli Studi di Napoli, Sezione di Reumatologia.
出版信息
Reumatismo. 2006 Apr-Jun;58(2):112-5. doi: 10.4081/reumatismo.2006.112.
OBJECTIVE
To investigate the Italian version of HAQ-DI (Health Assessment Questionnaire Disability Index) in systemic sclerosis (SSc).
METHODS
121 SSc patients, satisfying ACR criteria for the classification of this disease and consecutively admitted to a tertiary Unit, were invited to participate to the study. The Italian version of HAQ-DI, as validated in rheumatoid arthritis, was administered to each of them. The relationships between this parameter and the following disease aspects: disease subset, wide extent of skin sclerosis, joint contractures, myopathy, active digital ulcers, were investigated.
RESULTS
HAQ-DI resulted to be 0.772+/-0.074 (mean+/-SE) Statistically significant differences in HAQ-DI scores were detected between patients with and respectively without wide extent of skin sclerosis (ie modified Rodnan skin score >14) (1.158+/-0.176 vs 0.652+/-0.076; P<0.001), joints contractures (0.839+/-0.076 vs 0.159+/-0.147; P<0.001), myopathy (1.875+/-0.184 vs 0.656+/-0.071; P<0.001), digital ulcers (1.047+/-0.135 vs 0.680+/-0.109; P=0.006).
CONCLUSIONS
Our data support the validity of the Italian version of HAQ-DI in SSc.
目的
研究健康评估问卷残疾指数（HAQ-DI）意大利语版在系统性硬化症（SSc）中的应用。
方法
邀请121例符合美国风湿病学会（ACR）该疾病分类标准且连续入住三级医疗单位的SSc患者参与研究。向每位患者发放经类风湿关节炎验证的HAQ-DI意大利语版问卷。研究该参数与以下疾病方面的关系：疾病亚型、广泛皮肤硬化程度、关节挛缩、肌病、活动性指端溃疡。
结果
HAQ-DI结果为0.772±0.074（均值±标准误）。在皮肤广泛硬化（即改良Rodnan皮肤评分>14）的患者与无此情况的患者之间，HAQ-DI评分存在统计学显著差异（1.158±0.176 vs 0.652±0.076；P<0.001），关节挛缩患者与无关节挛缩患者之间（0.839±0.076 vs 0.159±0.147；P<0.001），肌病患者与无肌病患者之间（1.875±0.184 vs 0.656±0.071；P<0.001），指端溃疡患者与无指端溃疡患者之间（1.047±0.135 vs 0.680±0.109；P=0.006）。
结论
我们的数据支持HAQ-DI意大利语版在SSc中的有效性。
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