使用共焦扫描激光检眼镜进行口服荧光素血管造影与使用数码眼底照相机进行静脉注射荧光素血管造影的比较评估。

Comparative evaluation of oral fluorescein angiography using the confocal scanning laser ophthalmoscope and digital fundus camera with intravenous fluorescein angiography using the digital fundus camera.

作者信息

Azad Raj Vardhan, Baishya Bipul, Pal Nikhil, Sharma Yog Raj, Kumar Atul, Vohra Rajpal

机构信息

Vitreo-Retina Services, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Clin Exp Ophthalmol. 2006 Jul;34(5):425-9. doi: 10.1111/j.1442-9071.2006.01243.x.

DOI:10.1111/j.1442-9071.2006.01243.x

PMID:16872337

Abstract

BACKGROUND

To study the efficacy of oral fluorescein angiography (FA) with confocal scanning laser ophthalmoscope (CSLO).

METHODS

Ten patients each of choroidal neovascular membrane, central serous retinopathy, diabetic retinopathy and five normal subjects were evaluated with group 1 - intravenous FA using digital fundus camera (DFC); group 2 - oral FA using DFC; and group 3 - oral FA using CSLO.

RESULTS

Third-order branch vessels were identified in 85.7% eyes in group 3 versus 51.4% in group 2 (P = 0.004), image quality was comparable to intravenous FA in 77.1% in group 3 versus 48.5% in group 2 (P = 0.02) and margin delineation was better in 80% eyes in group 3 versus 35% in group 2 (P = 0.01). The foveal avascular zone was clear and intact in 54.2% eyes in group 3 versus 37.1% in group 2 (P = 0.14) and 57.1% in group 1 (P = 0.8).

CONCLUSION

Oral FA using CSLO is superior to oral FA using DFC and comparable to intravenous FA using DFC in terms of image quality, branch retinal vessel identification and margin delineation.

摘要

背景

研究使用共焦扫描激光眼底镜（CSLO）进行口服荧光素血管造影（FA）的疗效。

方法

对10例脉络膜新生血管膜、中心性浆液性视网膜病变、糖尿病视网膜病变患者以及5名正常受试者进行评估，分为三组：第1组——使用数码眼底照相机（DFC）进行静脉注射FA；第2组——使用DFC进行口服FA；第3组——使用CSLO进行口服FA。

结果

第3组85.7%的眼睛识别出三级分支血管，而第2组为51.4%（P = 0.004）；第3组77.1%的眼睛图像质量与静脉注射FA相当，第2组为48.5%（P = 0.02）；第3组80%的眼睛边缘勾勒更好，第2组为35%（P = 0.01）。第3组54.2%的眼睛黄斑无血管区清晰完整，第2组为37.1%（P = 0.14），第1组为57.1%（P = 0.8）。