Paziault Marylène, Terrade François-Xavier, Fermeaux Véronique, Pascal Barbara, Darreye Ghislaine, Dussartre Catherine, Gilquin Martial, Labrousse François, Tubiana-Mathieu Nicole
Association pour le dépistage du cancer du sein, 22 avenue Jean-Gagnant, 87037 Limoges Cedex.
Bull Cancer. 2006 Jul;93(7):731-6.
We report pathological characteristics of screen detected breast cancers versus breast cancers diagnosed outside the official breast screening program. The breast cancer screening program was organised in the county of Haute-Vienne and a pathological record was established in the Association de dépistage des cancers du sein (ADCS 87). Three hundred and thirty three cases were recorded in 50 to 74 years-old women who had been screened (74 were interval cancers), six hundred and eighty seven in 50 to 74 years-old women without screening and three hundred and fifteen in women under 50. No difference in ductal carcinoma in situ or histological type was noted but tumor size and lymph node involvement presented significantly more favorable prognosis in screen detected breast cancers. This study confirms the potential benefit of screening in breast cancer.
我们报告了通过筛查发现的乳腺癌与在官方乳腺癌筛查项目之外确诊的乳腺癌的病理特征。乳腺癌筛查项目在奥弗涅省进行组织,并在乳腺癌筛查协会(ADCS 87)建立了病理记录。在接受筛查的50至74岁女性中记录了333例病例(74例为间期癌),在未接受筛查的50至74岁女性中有687例,在50岁以下女性中有315例。原位导管癌或组织学类型未发现差异,但在筛查发现的乳腺癌中,肿瘤大小和淋巴结受累情况显示出明显更有利的预后。本研究证实了乳腺癌筛查的潜在益处。