Young Yi-Ho
Department of Otolaryngology, National Taiwan University Hospital, 1 Chang-Te Street, Taipei, Taiwan.
J Biomed Sci. 2006 Nov;13(6):745-51. doi: 10.1007/s11373-006-9106-6. Epub 2006 Aug 10.
By easily stimulating the ear with loud sound and recording on tonically contracted neck muscles, vestibular evoked myogenic potential (VEMP) test can reflect inner ear function other than the cochlea and semicircular canal. This expands the test battery for clinicians to explore saccular disease, adding a potential usefulness to the sacculo-collic reflex. The ideal stimulation mode for VEMPs is as follows: 95 dB tone bursts, frequency 500 Hz, stimulation repetition rate 5 Hz, rise/fall time 1 ms, plateau 2 ms, binaural stimulation with bilateral recordings. Animal model using guinea pigs has been established, which sets the stage for useful future studies investigating VEMPs in guinea pigs that would appear to resemble human VEMP responses. Clinically, VEMP test has been widely used in central and peripheral vestibular disorders.
通过用大声刺激耳朵并记录紧张收缩的颈部肌肉,前庭诱发肌源性电位(VEMP)测试可以反映除耳蜗和半规管之外的内耳功能。这扩展了临床医生探索球囊疾病的测试方法,增加了球囊 - 颈反射的潜在用途。VEMP的理想刺激模式如下:95分贝短纯音,频率500赫兹,刺激重复率5赫兹,上升/下降时间1毫秒,平台期2毫秒,双侧记录的双耳刺激。已经建立了使用豚鼠的动物模型,这为未来研究豚鼠的VEMP奠定了基础,豚鼠的VEMP反应似乎与人类相似。临床上,VEMP测试已广泛用于中枢性和外周性前庭疾病。