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与隐匿性磷尿性间叶肿瘤相关的致癌性骨软化症:临床-放射学-病理学相关性及超微结构研究

Oncogenic osteomalacia associated with an occult phosphaturic mesenchymal tumour: clinico-radiologico-pathological correlation and ultrastructural studies.

作者信息

Cheung F M F, Ma L, Wu W C, Siu T H, Choi P T, Tai Y P

机构信息

Department of Pathology, Pamela Youde Nethersole Eastern Hospital, Chai Wan, Hong Kong.

出版信息

Hong Kong Med J. 2006 Aug;12(4):319-21.

Abstract

A middle-aged man presented with bone pain at multiple sites due to tumour-induced osteomalacia. The underlying occult phosphaturic mesenchymal tumour was identified by octreotide scan 5 years after presentation and confirmed by computed tomography. Tumour resection resulted in normalisation of blood chemistry and bone densitometry. Clinico-radiologico-pathological correlation and ultrastructural studies of the tumour threw light on the pathogenesis and pathophysiology of this rare disease.

摘要

一名中年男性因肿瘤诱导的骨软化症出现多处骨痛。潜在的隐匿性磷酸尿性间叶肿瘤在出现症状5年后通过奥曲肽扫描得以识别,并经计算机断层扫描证实。肿瘤切除后血液化学指标和骨密度测定恢复正常。对该肿瘤的临床-放射-病理相关性及超微结构研究揭示了这种罕见疾病的发病机制和病理生理学。

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