Eysker M, van Doorn D C K, Lems S N, Weteling A, Ploeger H W
Afdeling Klinische Infectiologie, Departement Infectieziekten en Immunologie, Faculteit der Diergeneeskunde, Universiteit Utrecht, Postbus 80.165, 3508 TD Utrecht.
Tijdschr Diergeneeskd. 2006;131(14-15):524-30.
Due to excessive and inappropriate use of dewormers anthelmintic resistance has developed as a significant problem in horse parasites in the Netherlands. Since it is unlikely that new classes of anthelmintics against horse nematodes will be introduced in the near future, it is important to use the present drugs wisely. Veterinarians should advice horse owners about worm control programs with a more targeted approach. The number of anthelmintic treatments should be reduced and, through selective anthelmintic treatments, further development of anthelmintic resistance should be delayed. Preferably, horses with a low faecal egg count should not be treated at all to ascertain a reduction of the selection pressure for anthelmintic resistance. The propensity for low faecal egg counts is hereditary. This implies that mature horses with consistent low egg counts can be detected by faecal examination and that it is not necessary to repeat faecal examination each time in these animals. New horses on the farm should always be dewormed on arrival and should be introduced only after the efficacy of treatment has been determined. Anthelmintic resistance can also be introduced with the arrival of a new animal that is infected with drug-resistant parasites.
由于驱虫剂的过度和不当使用,抗蠕虫药耐药性已成为荷兰马匹寄生虫中的一个重大问题。鉴于近期不太可能引入针对马线虫的新型驱虫剂,明智地使用现有药物非常重要。兽医应就采用更具针对性的方法的蠕虫控制计划向马主提供建议。应减少驱虫治疗的次数,并且通过选择性驱虫治疗,应延缓抗蠕虫药耐药性的进一步发展。最好根本不治疗粪便虫卵计数低的马匹,以确定降低抗蠕虫药耐药性的选择压力。粪便虫卵计数低的倾向是可遗传的。这意味着可以通过粪便检查检测出粪便虫卵计数持续较低的成年马,并且没有必要每次都对这些动物重复进行粪便检查。农场中的新马到达时应始终进行驱虫,并且仅在确定治疗效果后才引入。耐药寄生虫感染的新动物的到来也可能引入抗蠕虫药耐药性。