欧洲儿童癌症生存率的地理比较（1988 - 1997年）：来自儿童癌症自动信息系统项目的报告

Geographical comparison of cancer survival in European children (1988-1997): report from the Automated Childhood Cancer Information System project.

作者信息

Sankila R, Martos Jiménez M C, Miljus D, Pritchard-Jones K, Steliarova-Foucher E, Stiller C

机构信息

Finnish Cancer Registry-Institute for Statistical and Epidemiological Cancer Research, Liisankatu 21 B, 00170 Helsinki, Finland.

出版信息

Eur J Cancer. 2006 Sep;42(13):1972-80. doi: 10.1016/j.ejca.2006.05.013.

DOI:10.1016/j.ejca.2006.05.013

PMID:16919765

Abstract

The aim of this study was to assess regional survival differences among childhood cancer patients in Europe. For this exercise, the Automated Childhood Cancer Information System (ACCIS) database was utilised. Survival data from 54 population-based cancer registries on 49,651 childhood cancer patients aged 0-14 years and diagnosed in 1988-1997 were analysed using life-table method. Overall, the 5-year survival was 72% among all patients, varying from 62% to 77% between the five geographical regions. The East region generally had lower survival rates than the rest of Europe. The geographical differences indicate the need for more co-ordination, systematisation and standardisation in diagnosis, referral and the treatment of childhood cancers in Europe. Increase of resources is necessary to improve the lower survival in the East region. Continuing data collection on a European level will facilitate monitoring of population-based survival of childhood cancer patients.

摘要

本研究的目的是评估欧洲儿童癌症患者的区域生存差异。为此，使用了儿童癌症自动信息系统（ACCIS）数据库。采用生命表法分析了来自54个基于人群的癌症登记处的生存数据，这些数据涉及1988 - 1997年诊断的49651名0至14岁的儿童癌症患者。总体而言，所有患者的5年生存率为72%，五个地理区域之间的生存率从62%到77%不等。东部地区的生存率普遍低于欧洲其他地区。地理差异表明，欧洲在儿童癌症的诊断、转诊和治疗方面需要更多的协调、系统化和标准化。增加资源对于提高东部地区较低的生存率是必要的。在欧洲层面持续收集数据将有助于监测儿童癌症患者基于人群的生存率。