Blomfeldt Richard, Törnkvist Hans, Ponzer Sari, Söderqvist Anita, Tidermark Jan
Karolinska Institutet, Department of Orthopaedics at Stockholm Söder Hospital, Stockholm, SE-118 83. Sweden.
Acta Orthop. 2006 Aug;77(4):638-43. doi: 10.1080/17453670610012728.
Recent randomized controlled trials have shown that for the active and lucid elderly patient with a displaced femoral neck fracture, a primary total hip replacement (THR) is superior to internal fixation (IF) regarding the need for secondary surgery, hip function and health-related quality of life (HRQoL). Despite the high failure rate for IF, the method is still recommended for this patient cohort by some authors. One argument is that if IF fails, there is always the possibility of performing a secondary salvage THR. The main aim of our study was to determine whether a primary THR, as compared to a secondary THR after failed IF, gives a better outcome after 2 years.
We compared outcome for 43 patients with a primary THR to the outcome for 41 patients who were treated with a secondary THR after failed IF. All patients (mean age 80 years) were lucid and had a displaced femoral neck fracture. Hip function (Charnley score) and health-related quality of life (HRQoL, EQ5D) were assessed 2 years after the THR procedure.
Hip function was better in the primary THR group: the mean Charnley score was 15/18 as compared to 13/18 in the secondary THR group (p < 0.001). The patients with failed IF who later underwent a secondary THR experienced a more pronounced decrease in HRQoL (EQ-5D index score) during the first year of treatment compared to patients in the primary THR group, with a difference of 0.25 in the EQ-5D index score at the 4-month follow-up (p = 0.02).
We found that a secondary THR after failed IF results in inferior hip function compared to a primary THR for a displaced femoral neck fracture in the active and lucid elderly patient. Moreover, the patients with failed IF had to undergo at least one re-operation and experienced a significant reduction in HRQoL before the salvage THR.
近期的随机对照试验表明,对于活跃且神志清醒的老年股骨颈移位骨折患者,在二次手术需求、髋关节功能及健康相关生活质量(HRQoL)方面,初次全髋关节置换术(THR)优于内固定术(IF)。尽管IF失败率高,但一些作者仍推荐该方法用于这一患者群体。一种观点认为,如果IF失败,总有可能进行二次挽救性THR。我们研究的主要目的是确定与IF失败后进行二次THR相比,初次THR在2年后是否能带来更好的结果。
我们将43例行初次THR患者的结果与41例IF失败后行二次THR患者的结果进行了比较。所有患者(平均年龄80岁)均神志清醒且有股骨颈移位骨折。在THR手术后2年评估髋关节功能(Charnley评分)和健康相关生活质量(HRQoL,EQ5D)。
初次THR组的髋关节功能更好:平均Charnley评分为15/18,而二次THR组为13/(p < 0.001)。与初次THR组患者相比,IF失败后行二次THR的患者在治疗的第一年HRQoL(EQ-5D指数评分)下降更为明显,在4个月随访时EQ-5D指数评分差异为0.25(p = 0.02)。
我们发现,对于活跃且神志清醒的老年股骨颈移位骨折患者,IF失败后进行二次THR与初次THR相比,髋关节功能较差。此外,IF失败的患者在挽救性THR之前必须至少接受一次再次手术,且HRQoL显著降低。