Cu(II)-catalyzed selective aerobic oxidation of alcohols under mild conditions.

Aerobic Alcohol Oxidation. An efficient four-component system consisting of acetamido-TEMPO/Cu(ClO4)2/TMDP/DABCO in DMSO has been developed for room-temperature aerobic alcohol oxidation. Under the optimal conditions, various alcohols could be converted into their corresponding aldehydes or ketones in good to excellent yields. The newly developed catalytic system could also be recycled and reused for three runs without any significant loss of catalytic activity.