热带地区——基于时空显微镜图像的反应扩散模型的参数估计与模拟
Tropical--parameter estimation and simulation of reaction-diffusion models based on spatio-temporal microscopy images.
作者信息
Ulrich Markus, Kappel Constantin, Beaudouin Joel, Hezel Stefan, Ulrich Jochen, Eils Roland
机构信息
Department of Theoretical Bioinformatics, German Cancer Research Center Im Neuenheimer Feld 580, 69120 Heidelberg, Germany.
出版信息
Bioinformatics. 2006 Nov 1;22(21):2709-10. doi: 10.1093/bioinformatics/btl456. Epub 2006 Aug 29.
UNLABELLED
Tropical is a software for simulation and parameter estimation of reaction-diffusion models. Based on spatio-temporal microscopy images, Tropical estimates reaction and diffusion coefficients for user-defined models. Tropical allows the investigation of systems with an inhomogeneous distribution of molecules, making it well suited for quantitative analyses of microscopy experiments such as fluorescence recovery after photobleaching (FRAP).
AVAILABILITY
Tropical is available free of charge for academic use at http://www.dkfz.de/tbi/projects/modellingAndSimulationOfCelluarSystems/tropical.jsp after signing a material transfer agreement.
未标注
Tropical是一款用于反应扩散模型模拟和参数估计的软件。基于时空显微镜图像，Tropical可为用户定义的模型估计反应和扩散系数。Tropical可用于研究分子分布不均匀的系统，非常适合对诸如光漂白后荧光恢复（FRAP）等显微镜实验进行定量分析。
可用性
签署材料转让协议后，可在http://www.dkfz.de/tbi/projects/modellingAndSimulationOfCelluarSystems/tropical.jsp免费获取供学术使用的Tropical。
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