[Current research in adequate treatment by Osteoporosis Research Group].

In 2002, Adequate Treatment of Osteoporosis (A-TOP) Research Group was organized to obtain the evidence for treatment of osteoporosis in Japan. The group has designed and carried out an intervention trial plan, Japanese Osteoporosis Intervention Trial (JOINT)-02 to demonstrate the possible combination effect of alendronate plus active vitamin D(3). In this report, we summarize the past activity and the perspective of the future of the A-TOP research group.