Halim Hadi, Rasyid Ahmad, Ahmad Zen
Division of Pulmonology, Departement of Internal Medicine, Dr. Mohammad Hoesin Hospital Palembang, South Sumatra.
Acta Med Indones. 2006 Jul-Sep;38(3):130-4.
To obtain an overview of the problem and to know the success and result of DOTS method in tuberculosis treatment.
Application of DOTS at the hospital was done every Monday during working hours at the outpatient clinic pulmonology clinic Department of Internal Medicine of Dr. Mohammad Hoesin Hospital in Palembang, Indonesia. Selection of patients was done at the general outpatient clinic. Patients suspected with pulmonary TB were clinically investigated with the sputum Acid Fast Bacilli 3x test (spot, morning, spot). If the sputum tests were negative, the patients underwent Chest X Ray. Patients with complete data were referred to the DOTS clinic. Hospital nurses and doctor residents from internal medicine filled up the medical records, TB form and registration of identity card, determined the Observer of Medicine Consumption (PMO) and provided the "Informed Consent". Education and motivation on the problem of tuberculosis were conducted by doctors and nurses. Finally, patients are requested to consume medicine by their observer with assistance from the pharmacist, and were given DOTS medicine for 1 - 2 weeks.
At the end of August 2002, 517 patients had completed treatment. The cure rate from positive sputum AFB was 82.17% (295 from 359 patients); 87.7% for category I (221 from 252 patients) and 69.2% for category II (74 from 107 patients). This can be increased to 85.3.% (295/344; Total), 92.5% (221/239 ; category I) and 70.5% (74/105; category II), those patients transfered out were not included in the denomination. The percentage of those who completed category III treatment was 91.8% (145 from 158 patients), with a drop - out/default rate of 6.2%.
DOTS strategy in hospital was done by DOTS team consisted of doctors, nurses, assistant pharmacist and health workers. The number of TB cases in Moh. Hoesin Hospital Palembang in category I is more than category II/III, RK Charitas Category III is more than category I/II which are unemployed, primary school and productive ages. DOTS treatment on 2006 was done by FDC (Fixed Dose Combination).
全面了解问题,并知晓直接观察短程治疗(DOTS)方法在结核病治疗中的成效与结果。
在印度尼西亚巨港穆罕默德·霍辛医院内科肺病门诊,每周一工作时间于医院开展DOTS应用。患者在普通门诊进行筛选。疑似肺结核患者接受痰涂片抗酸杆菌3次检测(即时痰、晨痰、即时痰)的临床检查。若痰检呈阴性,则对患者进行胸部X光检查。数据完整的患者被转至DOTS诊所。医院护士和内科住院医生填写病历、结核病表格及身份证登记信息,确定服药监督员(PMO)并提供“知情同意书”。医生和护士就结核病问题开展教育与宣传工作。最后,要求患者在药剂师协助下由其服药监督员监督服药,并给予1至2周的DOTS药物。
2002年8月底,517例患者完成治疗。痰涂片抗酸杆菌阳性患者的治愈率为82.17%(359例患者中的295例);I类患者治愈率为87.7%(252例患者中的221例),II类患者治愈率为69.2%(107例患者中的74例)。若不包括转出患者,总体治愈率可提高至85.3%(295/344),I类患者治愈率为92.5%(221/239),II类患者治愈率为70.5%(74/105)。III类治疗完成率为91.8%(158例患者中的145例),脱落/违约率为6.2%。
医院的DOTS策略由包括医生、护士、药剂师助理和卫生工作者的DOTS团队实施。巨港穆罕默德·霍辛医院I类结核病病例数多于II/III类,慈善机构RK的III类病例数多于I/II类,这些病例多为失业、小学学历及处于工作年龄段的人群。2006年的DOTS治疗采用了固定剂量复合制剂(FDC)。