Unusual macular lesions in a patient with neurofibromatosis type-1.

BACKGROUND

Retinal involvement in neurofibromatosis type-1 (NF-1) is rare.

METHODS

We present a case report of a 49-year-old man with neurofibromatosis who developed bilateral macular lesions associated with gradual reduction of visual acuity.

RESULTS

Electrophysiology revealed an absent pattern electroretinogram. Fluorescein angiography demonstrated mottled hyperfluorescence of the maculae in the early-phase fluorescein angiogram followed by late staining of the lesions.

CONCLUSIONS

Our patient had unusual bilateral macular lesions which had some features suggestive of adult-onset foveomacular vitelliform dystrophy. To the best of our knowledge, there have been no previous reports of such macular lesions occurring in association with NF-1.