Caloglu Murat, Yurut-Caloglu Vuslat, Altaner Semsi, Huseyinova Gulara, Unlu Ercument, Karagol Hakan, Uzal Cem
Department of Radiation Oncology, Faculty of Medicine, Trakya University, Edirne, Turkey.
Onkologie. 2006 Sep;29(8-9):388-90. doi: 10.1159/000095029. Epub 2006 Sep 5.
Oncocytic carcinoma is a rare tumor of major salivary glands. Despite being described 5 decades ago, not much is known about these rare tumors. Histochemical or electron microscopic confirmation of the oncocytic nature of the tumor cell is needed for differential diagnosis. The main treatment modality is surgery with or without adjuvant radiotherapy. Malignant oncocytomas have the potential risk of developing distant metastases and demand long term follow-up after therapy.
A 58-year old man presented with a recurrent mass in the left parotid gland with a prior diagnosis of monomorphic adenoma in the same localization which had been treated by tumor excision in July 2002. Left superficial parotidectomy followed by radiotherapy into tumor bed and upper neck were carried out in September 2004. To date, he has had no evidence of recurrence for 14 months.
For an accurate approach in the management of patients, oncocytic adenocarcinoma should be considered in the differential diagnosis of lesions of the parotid gland, most of which are benign.
嗜酸细胞癌是大唾液腺的一种罕见肿瘤。尽管在50年前就有相关描述,但对于这些罕见肿瘤仍知之甚少。鉴别诊断需要通过组织化学或电子显微镜检查来确认肿瘤细胞的嗜酸细胞性质。主要治疗方式是手术,可辅以或不辅以放疗。恶性嗜酸细胞瘤有发生远处转移的潜在风险,治疗后需要长期随访。
一名58岁男性,左腮腺出现复发性肿块,此前于2002年7月在同一部位诊断为单形性腺瘤,并接受了肿瘤切除治疗。2004年9月进行了左侧腮腺浅叶切除术,随后对肿瘤床和上颈部进行了放疗。迄今为止,他已14个月无复发迹象。
为了准确处理患者,在腮腺病变的鉴别诊断中应考虑嗜酸细胞腺癌,其中大多数病变是良性的。