Perlmutter Adam E, Morabito Rocco, Tarry William F
Division of Urology, West Virginia University School of Medicine, Morgantown, West Virginia 26506, USA.
Urology. 2006 Sep;68(3):648-51. doi: 10.1016/j.urology.2006.03.079. Epub 2006 Sep 18.
To assess whether the age at which the initial hypospadias repair is performed influences the complication rate of hypospadias repair.
The records of 325 consecutive patients who underwent initial hypospadias repair were reviewed. The patients with glanular and coronal hypospadias underwent repair with either meatoplasty and glanuloplasty or a glans approximation procedure. Patients with subcoronal hypospadias and penile hypospadias underwent repair with tubularized incised plate urethroplasty. The patients were divided into 6-month age groups, and the complication rates were analyzed by age group using the chi-square test.
A total of 325 hypospadias repairs were performed from January 1999 to January 2005 by a single surgeon. Of the 325 cases, 194 tubularized incised plate procedures were performed, 69 meatoplasty and glanuloplasty procedures were performed, and 53 glans approximation procedures were performed. Nine tubularized island flap urethroplasties performed for penoscrotal hypospadias were excluded because we did not perform a significant number of proximal urethroplasties. Nineteen patients (6.0%) developed urethrocutaneous fistulas and six (1.9%) demonstrated dehiscence. Overall, 2 patients (2.2%) who underwent surgical repair within the first 6 months of age developed complications compared with 23 patients (10.3%) who underwent initial hypospadias repair when they were older than 6 months of age (P = 0.006).
Tubularized incised plate, meatoplasty and glanuloplasty, and glans approximation urethroplasty are all excellent options for the surgical correction of hypospadias in the appropriately selected patient. The results of our study have indicated that complications are minimized when hypospadias repair is performed when the patient is 4 to 6 months of age.
评估首次进行尿道下裂修复手术的年龄是否会影响尿道下裂修复的并发症发生率。
回顾了325例连续接受首次尿道下裂修复手术患者的记录。阴茎头型和冠状沟型尿道下裂患者采用尿道口成形术和阴茎头成形术或阴茎头靠拢手术进行修复。冠状沟下型和阴茎型尿道下裂患者采用管状切开板尿道成形术进行修复。将患者按6个月的年龄分组,采用卡方检验按年龄组分析并发症发生率。
1999年1月至2005年1月,由一名外科医生共进行了325例尿道下裂修复手术。在这325例病例中,进行了194例管状切开板手术,69例尿道口成形术和阴茎头成形术,以及53例阴茎头靠拢手术。因近端尿道成形术数量不多,排除了9例为阴茎阴囊型尿道下裂进行的管状岛状皮瓣尿道成形术。19例患者(6.0%)出现尿道皮肤瘘,6例(1.9%)出现裂开。总体而言,6个月龄内接受手术修复的2例患者(2.2%)出现并发症,而6个月龄后接受首次尿道下裂修复的23例患者(10.3%)出现并发症(P = 0.006)。
对于经过适当选择的患者,管状切开板、尿道口成形术和阴茎头成形术以及阴茎头靠拢尿道成形术都是尿道下裂手术矫正的极佳选择。我们的研究结果表明,在患者4至6个月龄时进行尿道下裂修复,并发症可降至最低。