Hopkins William D, Dunham Leslie, Cantalupo Claudio, Taglialatela Jared
Department of Psychology, Agnes Scott College, Decatur, GA 30030, USA.
Cereb Cortex. 2007 Aug;17(8):1757-65. doi: 10.1093/cercor/bhl086. Epub 2006 Sep 29.
It has been suggested from studies in human subjects that sex, handedness, and brain asymmetries influence variation in corpus callosum (CC) size and these differences reflect the degree of connectivity between homotopic regions of the left and right cerebral hemispheres. Here we report that handedness is associated with variation in the size of the CC in chimpanzees. We further report that variation in brain asymmetries in a cortical region homologous to Broca's area is associated with the size of the CC but differs for right- and left-handed individuals. Collectively, the results suggest that individual differences in functional and neuroanatomical asymmetries are associated with CC variation not just in humans but also in chimpanzees and therefore may reflect a common neural basis for laterality in these 2 species.
对人类受试者的研究表明，性别、用手习惯和大脑不对称性会影响胼胝体（CC）大小的变化，这些差异反映了左右大脑半球同位区域之间的连接程度。在此我们报告，用手习惯与黑猩猩CC大小的变化有关。我们还报告，与布洛卡区同源的皮质区域的大脑不对称性变化与CC大小有关，但左右手习惯不同的个体存在差异。总体而言，这些结果表明，功能和神经解剖学不对称性的个体差异不仅与人类的CC变化有关，也与黑猩猩的CC变化有关，因此可能反映了这两个物种偏侧性的共同神经基础。
