Stover Bert D, Turner Judith A, Franklin Gary, Gluck Jeremy V, Fulton-Kehoe Deborah, Sheppard Lianne, Wickizer Thomas M, Kaufman Joel, Egan Kathleen
Department of Environmental & Occupational Health Sciences, University of Washington School of Public Health and Community Medicine, Seattle, 98103, USA.
J Pain. 2006 Oct;7(10):718-25. doi: 10.1016/j.jpain.2006.03.004.
Prescription of opioids for nonmalignant musculoskeletal pain has increased substantially in recent years, but there is little information on the incidence of, or factors associated with, such prescription for work-related back pain. In a prospective cohort study (N = 1,067), we examined associations between worker sociodemographic and other characteristics and opioid prescription within six weeks of the first medical visit for workers' compensation claims for work loss due to back injury. We examined administrative, pharmacy, and worker-reported data. In bivariate logistic regression models, Hispanics were less likely than non-Hispanic whites to receive opioid prescriptions, and very high body mass index, daily tobacco use, greater pain and physical disability, pain radiating below the knee, injury severity categorizations (from medical records) of major sprain and radiculopathy, and worse mental health were associated with opioid prescription. Adjusting for demographics, pain intensity, and physical disability, opiate prescription was significantly associated with daily tobacco use, pain radiating below the knee, and injury severity categories (major sprain and radiculopathy). Knowledge of worker characteristics associated with early opioid prescription may be useful in future studies of the role of early pain treatment in influencing subsequent course of pain and disability among workers with back injuries.
Little is known about patient characteristics that may influence physicians' decisions concerning prescription of opioids for acute back pain. Not surprisingly, workers with more severe back injuries are more likely to be prescribed opioids, but reasons for prescription disparities based on ethnicity and tobacco use warrant further study.
近年来,用于非恶性肌肉骨骼疼痛的阿片类药物处方量大幅增加,但关于因工作相关背痛而开具此类处方的发生率或相关因素的信息却很少。在一项前瞻性队列研究(N = 1067)中,我们调查了工人的社会人口统计学特征及其他特征与首次因背部损伤导致工作损失而提出工伤赔偿申请后六周内阿片类药物处方之间的关联。我们研究了行政、药房及工人报告的数据。在二元逻辑回归模型中,西班牙裔比非西班牙裔白人获得阿片类药物处方的可能性更小,而且极高的体重指数、每日吸烟、更严重的疼痛和身体残疾、膝盖以下放射性疼痛、(根据病历)严重扭伤和神经根病的损伤严重程度分类以及较差的心理健康状况都与阿片类药物处方有关。在对人口统计学、疼痛强度和身体残疾进行调整后,阿片类药物处方与每日吸烟、膝盖以下放射性疼痛以及损伤严重程度分类(严重扭伤和神经根病)显著相关。了解与早期阿片类药物处方相关的工人特征可能有助于未来研究早期疼痛治疗对背部受伤工人后续疼痛和残疾病程的影响。
关于可能影响医生对急性背痛开具阿片类药物处方决策的患者特征,我们知之甚少。不出所料,背部损伤更严重的工人更有可能被开具阿片类药物,但基于种族和吸烟情况的处方差异原因值得进一步研究。