Gerber Andreas C, Weiss Markus
Department of Anaesthesia, University Children's Hospital, Zurich, Switzerland.
Curr Opin Anaesthesiol. 2003 Jun;16(3):315-20. doi: 10.1097/00001503-200306000-00012.
Postoperative apnoea is known to threaten preterm and ex-preterm infants undergoing surgery for inguinal hernia. Awake regional anaesthesia, initially spinal and later caudal anaesthesia have been suggested as effective techniques to avoid these complications. However, most herniotomies in this group of patients are still performed under general anaesthesia without deleterious consequences. Whereas some experts continue to claim advantages for awake regional over general anaesthesia for preterm infants, others consider awake regional anaesthesia to be an exclusive, technically difficult and unreliable technique of unconfirmed benefit.
It is appropriate to weigh the scarce available evidence that has been accumulated since 1984, and put it into perspective with new developments in paediatric general anaesthesia. The actual clinical significance of postoperative apnoea and improvements in neonatal and perioperative care and monitoring must also be reconsidered.
The available evidence does not allow unequivocal conclusions to be drawn or recommendations to be made. Awake regional anaesthesia for herniotomies in preterm infants has been found to be superior in most studies; however, it requires technical expertise and dedication on the part of the anaesthetist and surgeon. When light general anaesthesia with modern anaesthetic agents such as sevoflurane or desflurane is combined with a caudal block, postoperative apnoea is very rare, and can easily be recognized and managed with good postoperative monitoring and therapy.
已知术后呼吸暂停会威胁接受腹股沟疝手术的早产儿和前早产儿。有人提出清醒区域麻醉,最初是脊髓麻醉,后来是骶管麻醉,是避免这些并发症的有效技术。然而,这组患者中的大多数疝修补术仍在全身麻醉下进行,且没有不良后果。虽然一些专家继续声称清醒区域麻醉比全身麻醉对早产儿更具优势,但另一些人则认为清醒区域麻醉是一种独特、技术难度大且益处未得到证实的不可靠技术。
权衡自1984年以来积累的稀少现有证据,并结合小儿全身麻醉的新进展来正确看待它是合适的。术后呼吸暂停的实际临床意义以及新生儿和围手术期护理与监测的改善也必须重新考虑。
现有证据无法得出明确结论或提出建议。在大多数研究中,已发现早产儿疝修补术采用清醒区域麻醉更具优势;然而,这需要麻醉师和外科医生具备专业技术和敬业精神。当使用七氟醚或地氟醚等现代麻醉剂进行浅全身麻醉并联合骶管阻滞时,术后呼吸暂停非常罕见,并且通过良好的术后监测和治疗很容易识别和处理。