Datsenko B M, Pilipenko N I, Gubskiĭ V I, Sherlanov R A
Lab Delo. 1990(11):32-4.
A method for measuring circulating plasma volume (CPV) by diluting T-1824 indicator is described, making allowance for the exponential pattern of labeled serum albumin elimination from the vascular bed. The method consists in double collection of blood samples after intravenous injection of the indicator, computation of the constant of its extravasation rate, and extrapolation to the zero time. Analysis of the results obtained by this method and CPV values derived from the hematocrit and circulating blood volume--(CBV) estimated with the help of Albert table (1971), as well as with CPV value derived from the hematocrit and CBV measured by impedance method in 22 patients with slight uncomplicated ventral and diaphragmal hernias has demonstrated high linear correlation coefficients, +0.77 and +0.78 (p less than 0.01), respectively.
本文描述了一种通过稀释T-1824指示剂来测量循环血浆量(CPV)的方法,该方法考虑了标记血清白蛋白从血管床清除的指数模式。该方法包括在静脉注射指示剂后两次采集血样,计算其外渗速率常数,并外推至零时间。通过该方法获得的结果与根据血细胞比容和借助阿尔伯特表(1971年)估算的循环血量(CBV)得出的CPV值,以及与通过阻抗法测量的血细胞比容和CBV得出的CPV值,对22例轻度单纯性腹疝和膈疝患者进行分析,结果显示线性相关系数分别为+0.77和+0.78(p<0.01),具有高度相关性。