Thimmarayan S K, Rao V A, Gupta A
Department of Ophthalmology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India.
Eur J Ophthalmol. 2006 Sep-Oct;16(5):674-9. doi: 10.1177/112067210601600503.
To evaluate the safety and efficacy of mini-trabeculectomy in comparison to conventional trabeculectomy in primary open angle glaucoma (POAG).
A prospective interventional study of mini-trabeculectomy versus conventional trabeculectomy was undertaken on 60 eyes of 54 medically uncontrolled POAG patients requiring glaucoma surgery. They were divided into two groups: Group I underwent mini-trabeculectomy (30 eyes of 26 patients) and Group II underwent conventional trabeculectomy (30 eyes of 28 patients). All patients were followed up for at least 15 months. Statistical analysis was carried using Student's t test and paired t test for quantitative data and Pearson's chi-square test for qualitative data.
The mean intraocular pressures (IOP) at the end of 15 months of follow-up in Groups I and II were 15.80+/-4.3 mmHg and 16.13+/-3.3 mmHg versus mean preoperative IOP of 28.63+/-2.74 and 28.60+/-2.44, p<0.0001, respectively. The difference in IOP control was significant only at 6 months of follow up (13.65+/-3.45 versus 15.98+/-4.05, p=0.041). The complications and failure were comparatively less in Group I.
Mini-trabeculectomy is a safe and effective alternative to conventional trabeculectomy in terms of IOP control. A modified tunnel incision employed in mini-trabeculectomy may be responsible for avoiding some of the complications.
评估与传统小梁切除术相比,微型小梁切除术治疗原发性开角型青光眼(POAG)的安全性和有效性。
对54例药物治疗无法控制且需要进行青光眼手术的POAG患者的60只眼睛进行了一项关于微型小梁切除术与传统小梁切除术的前瞻性干预研究。他们被分为两组:第一组接受微型小梁切除术(26例患者的30只眼睛),第二组接受传统小梁切除术(28例患者的30只眼睛)。所有患者均随访至少15个月。使用学生t检验和配对t检验对定量数据进行统计分析,使用Pearson卡方检验对定性数据进行统计分析。
随访15个月结束时,第一组和第二组的平均眼压(IOP)分别为15.80±4.3 mmHg和16.13±3.3 mmHg,而术前平均IOP分别为28.63±2.74和28.60±2.44,p<0.0001。眼压控制的差异仅在随访6个月时显著(13.65±3.45对15.98±4.05,p = 0.041)。第一组的并发症和失败情况相对较少。
在眼压控制方面,微型小梁切除术是传统小梁切除术的一种安全有效的替代方法。微型小梁切除术中采用的改良隧道切口可能有助于避免一些并发症。