迷走神经刺激术治疗儿童难治性癫痫
Vagus nerve stimulation for intractable seizures in children.
作者信息
Saneto Russell P, Sotero de Menezes Marcio A, Ojemann Jeffrey G, Bournival Brian D, Murphy Patricia J, Cook William B, Avellino Anthony M, Ellenbogen Richard G
机构信息
Division of Pediatric Neurology, Children's Hospital and Regional Medical Center/University of Washington, Seattle, WA 98105, USA.
出版信息
Pediatr Neurol. 2006 Nov;35(5):323-6. doi: 10.1016/j.pediatrneurol.2006.06.005.
Forty-three children less than 12 years of age having intractable seizures were treated with vagus nerve stimulation. Five children were monitored for <12 months, 16 children for 12 to 17 months, and 22 children for > or =18 months with overall median seizure reduction of 55%. Thirty-seven percent had at least 90% reduction. Vagus nerve stimulation was effective in children with generalized, mixed, and partial medically refractory seizures.
43名12岁以下患有顽固性癫痫的儿童接受了迷走神经刺激治疗。5名儿童接受监测的时间小于12个月，16名儿童为12至17个月，22名儿童为大于或等于18个月，癫痫发作总体中位数减少了55%。37%的儿童癫痫发作减少至少90%。迷走神经刺激对全身性、混合型和部分药物难治性癫痫的儿童有效。
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