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新疆阿魏和托里阿魏根中的倍半萜香豆素

Sesquiterpene coumarins from the roots of Ferula sinkiangensis and Ferula teterrima.

作者信息

Yang Jun-Rong, An Zheng, Li Zhi-Hong, Jing Song, Qina Hai-Lin

机构信息

Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine (Peking Union Medical College), Ministry of Education, Beijing, PR China.

出版信息

Chem Pharm Bull (Tokyo). 2006 Nov;54(11):1595-8. doi: 10.1248/cpb.54.1595.

Abstract

Three new natural sesquiterpene coumarins, isofeterin (1), lehmannolol (3), sinkianone (4), and one known compound, lehmannolone (2), were isolated from the roots of Ferula teterrima and Ferula sinkiangensis. Their chemical structures were established on the basis of spectroscopic analysis, including X-ray crystallography and CD spectrum measurements for determining the absolute configuration of compound 2.

摘要

从准噶尔阿魏和新疆阿魏的根部分离出三种新的天然倍半萜香豆素,异费替林(1)、雷曼诺醇(3)、新疆阿魏酮(4),以及一种已知化合物雷曼诺酮(2)。它们的化学结构是在光谱分析的基础上确定的,包括用于确定化合物2绝对构型的X射线晶体学和圆二色光谱测量。

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