Beiruti N, Frencken J E, van 't Hof M A, van Palenstein Helderman W H
Regional WHO Demonstration, Training and Research Centre For Oral Health, Mezah, Damascus, Syria.
Community Dent Oral Epidemiol. 2006 Dec;34(6):403-9. doi: 10.1111/j.1600-0528.2006.00321.x.
The difference in preventing dentine lesion development between resin-based and glass ionomer sealant materials is unclear. Two recently published reviews were unable to conclude on the difference because the comparison was an exclusion criterion in one review and there were statistical shortcomings in the relevant papers in the other (Cochrane) review.
The aim of the present investigation was to carry out a systematic review on the caries-preventive effect of these two types of sealant materials under more liberal exclusion criteria concerning the statistical presentations in the publications.
Based on five exclusion criteria, the literature search in the electronic libraries PubMed and MEDLINE and the publications retrieved in the Cochrane review, revealed 12 eligible publications for analyses. A variety of glass ionomers and resin-based sealant materials had been applied in the included studies. Attributable risk (AR) was chosen rather than relative risk (RR), as used in the Cochrane review, because RR is very instable in a low caries population.
There was no consistent pattern observed with respect to the caries-preventive effect of either resin-based or glass ionomer sealants. Therefore, it was impossible to calculate an overall AR.
There is no evidence that either resin-based or glass ionomer sealant material is superior to the other in preventing dentine lesion development in pits and fissures over time.
树脂基封闭剂材料和玻璃离子封闭剂材料在预防牙本质病变发展方面的差异尚不清楚。最近发表的两篇综述未能就这种差异得出结论,因为在一篇综述中,这种比较是一项排除标准,而在另一篇(Cochrane)综述中,相关论文存在统计缺陷。
本研究的目的是在关于出版物中统计呈现的更宽松排除标准下,对这两种类型的封闭剂材料的防龋效果进行系统综述。
基于五项排除标准,在电子图书馆PubMed和MEDLINE中进行文献检索,并检索Cochrane综述中检索到的出版物,共筛选出12篇符合分析条件的出版物。纳入的研究中应用了多种玻璃离子和树脂基封闭剂材料。选择归因风险(AR)而非Cochrane综述中使用的相对风险(RR),因为RR在低龋患人群中非常不稳定。
在树脂基或玻璃离子封闭剂的防龋效果方面,未观察到一致的模式。因此,无法计算总体AR。
没有证据表明树脂基或玻璃离子封闭剂材料在预防窝沟牙本质病变随时间发展方面优于另一种材料。