Corneal staining after treatment with topical tetracycline.
作者信息
Lapid-Gortzak Ruth, Nieuwendaal Carla P, Slomovic Allan R, Spanjaard Lodewijk
机构信息
Department of Ophthalmology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
出版信息
Cornea. 2006 Sep;25(8):969-70. doi: 10.1097/01.ico.0000224647.66472.e3.
PURPOSE
The purpose of this paper is to report a case of corneal staining after treatment with topical tetracycline.
METHODS
A patient with crystalline keratopathy caused by Streptococcus viridans after corneal transplantation was treated topically with tetracycline eye drops, based on results of bacterial sensitivity testing. After 3 weeks of intensive treatment, the donor cornea was stained with a brownish hue, which was ascribed to the tetracycline drops.
RESULTS
One patient with crystalline keratopathy developed corneal staining after intensive treatment with topical tetracycline eye drops. After a year of follow-up, the staining of the cornea had not changed significantly.
CONCLUSION
Hourly topical tetracycline eye drops may induce corneal pigmentation. To our knowledge, this is the first published case report of corneal staining caused by tetracycline eye drops.
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