Sharaev P N, Botnikova E A, Ivanov V M, Zubarev O N, Malinin O V, Zubkova S V
Lab Delo. 1990(12):23-5.
A method of measuring urinary free, peptide- and protein-bound hydroxyproline is suggested. Adults were found to excrete 18 mumol of free, 155 mumol of peptide-bound, and 8 mumol of protein-bound hydroxyproline daily. In children daily urinary levels of free and peptide-bound hydroxyproline were higher. Data are presented on changes in various hydroxyproline forms in pneumonia, rheumatic fever, and hemorrhagic fever with the renal syndrome.
本文提出了一种测量尿中游离、肽结合和蛋白质结合羟脯氨酸的方法。研究发现，成年人每天排泄18微摩尔游离羟脯氨酸、155微摩尔肽结合羟脯氨酸和8微摩尔蛋白质结合羟脯氨酸。儿童尿中游离和肽结合羟脯氨酸的每日水平较高。文中给出了肺炎、风湿热和肾综合征出血热中各种羟脯氨酸形式变化的数据。
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