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类似维生素B12缺乏的铜缺乏性脊髓神经病:补充铜后磁共振成像表现部分缓解

Copper deficiency myeloneuropathy resembling B12 deficiency: partial resolution of MR imaging findings with copper supplementation.

作者信息

Goodman B P, Chong B W, Patel A C, Fletcher G P, Smith B E

机构信息

Department of Neurology, Mayo Clinic Scottsdale, Scottsdale, AZ 85259, USA.

出版信息

AJNR Am J Neuroradiol. 2006 Nov-Dec;27(10):2112-4.

Abstract

Copper deficiency has been associated with a clinical syndrome, myeloneuropathy. Radiographic changes resembling B(12) deficiency in the cervical spinal cord have been described. We present a case of copper deficiency myeloneuropathy, with cervical MR imaging findings resembling B(12) deficiency, which partially reversed following copper supplementation. This is, to our knowledge, the first described case of radiographic improvement with copper supplementation.

摘要

铜缺乏与一种临床综合征——脊髓神经病有关。已经描述了颈椎脊髓中类似维生素B12缺乏的影像学改变。我们报告一例铜缺乏性脊髓神经病病例,其颈椎磁共振成像表现类似于维生素B12缺乏,补充铜后部分症状得到改善。据我们所知,这是首例补充铜后影像学改善的病例报道。

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本文引用的文献

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Acquired hypocupremia after gastric surgery.胃手术后获得性低铜血症。
Clin Gastroenterol Hepatol. 2004 Dec;2(12):1074-9. doi: 10.1016/s1542-3565(04)00546-4.
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Copper deficiency myelopathy.铜缺乏性脊髓病
Arch Neurol. 2004 May;61(5):762-6. doi: 10.1001/archneur.61.5.762.
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Myelopathy due to copper deficiency.铜缺乏所致脊髓病
Neurology. 2003 Jul 22;61(2):273-4. doi: 10.1212/01.wnl.0000073542.02761.5f.

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