Han-Geurts I J M, Hop W C, Verhoef C, Tran K T C, Tilanus H W
Department of Surgery, Erasmus Medical Centre, Rotterdam, The Netherlands.
Br J Surg. 2007 Jan;94(1):31-5. doi: 10.1002/bjs.5283.
Feeding jejunostomy is frequently performed in patients undergoing oesophageal surgery, but can lead to serious complications. This prospective randomized trial compared the efficacy and complications of feeding jejunostomy with those of nasoduodenal tube feeding in oesophageal surgery.
Over an 18-month period, 150 consecutive patients undergoing oesophageal resection were randomized to participate in the trial. Enteral access was by jejunostomy in 79 patients and by nasoduodenal tube in 71. Enteral feeding was started on the first day after surgery.
Full enteral feeding took 3 days to be established in both groups. Minor catheter-related complications occurred in 28 patients (35 per cent) in the jejunostomy group, and in 21 (30 per cent) in the nasoduodenal group (P = 0.488). One patient had jejunostomy leakage that required reoperation. Enteral nutrition was given for a median of 11 days in the jejunostomy group and for 10 days in the nasoduodenal group. Nine patients who had a jejunostomy and five with a nasoduodenal tube did not tolerate full enteral feeding (P = 0.411).
Nasoduodenal tube feeding is safe and efficient after oesophageal resection.
空肠造口喂养常用于接受食管手术的患者,但可能导致严重并发症。本前瞻性随机试验比较了食管手术中空肠造口喂养与鼻十二指肠管喂养的疗效和并发症。
在18个月期间,150例连续接受食管切除术的患者被随机分组参与试验。79例患者通过空肠造口建立肠内通路,71例通过鼻十二指肠管。术后第一天开始肠内喂养。
两组均需3天建立完全肠内喂养。空肠造口组28例患者(35%)发生与导管相关的轻微并发症,鼻十二指肠组21例(30%)(P = 0.488)。1例患者空肠造口渗漏,需再次手术。空肠造口组肠内营养中位给予时间为11天,鼻十二指肠组为10天。9例空肠造口患者和5例鼻十二指肠管患者不能耐受完全肠内喂养(P = 0.411)。
食管切除术后鼻十二指肠管喂养安全有效。