Marson A G, Williamson P R, Taylor S, Maguire M, Chadwick D W
Division of Neurological Science, Clinical Sciences Centre for Research and Education, University of Liverpool, Liverpool, L9 7LJ, UK.
Neurology. 2006 Nov 28;67(10):1872-5. doi: 10.1212/01.wnl.0000244421.73986.09.
In the Multi-Centre Study of Early Epilepsy and Single Seizures (MESS), patients were randomly allocated to immediate or delayed antiepileptic drug treatment. For time to first seizure recurrence, MESS provides strong evidence of an effect for carbamazepine as monotherapy but mixed evidence of an effect for valproate.
在早期癫痫与单次发作多中心研究(MESS)中,患者被随机分配接受即刻或延迟抗癫痫药物治疗。对于首次癫痫复发时间,MESS提供了强有力的证据表明卡马西平作为单一疗法有效,但对于丙戊酸盐疗效的证据不一。