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弯孢霉角膜炎:1例人眼病例报告

Scytalidium keratitis: case report in a human eye.

作者信息

Farjo Qais A, Farjo Rand S, Farjo Ayad A

机构信息

Vision Associates, Toledo, OH 43615, USA.

出版信息

Cornea. 2006 Dec;25(10):1231-3. doi: 10.1097/01.ico.0000230323.28956.b9.

Abstract

PURPOSE

To describe the presentation and treatment of a case of an atypical reticular corneal infiltrate with surrounding immune-like ring in a young woman caused by Scytalidium fungal species.

METHODS

Interventional case report describing the clinical appearance, course, and treatment of Scytalidium keratitis.

RESULTS

A 21-year-old female equestrian with a history of soft contact lens wear was noted to have persistent keratitis and photophobia of the right eye after an injury with a volleyball. Although initially culture negative and responsive to topical steroids, the keratitis persisted, and repeat corneal scrapings and cultures revealed Scytalidium species. Treatment with topical amphotericin B 0.15% and oral fluconazole 200 mg twice daily eradicated the infection, and the patient had a final best-corrected visual acuity of 20/20.

CONCLUSION

Scytalidium species fungal organisms can cause an indolent keratitis. Intensive oral and topical antifungal therapy was successful in eradicating the infection.

摘要

目的

描述一名年轻女性因弯孢霉菌属真菌引起的伴有周围免疫样环的非典型网状角膜浸润病例的表现及治疗。

方法

干预性病例报告,描述弯孢霉菌角膜炎的临床表现、病程及治疗。

结果

一名21岁有软性隐形眼镜佩戴史的女骑手,在排球受伤后右眼出现持续性角膜炎和畏光。尽管最初培养结果为阴性且对局部类固醇治疗有反应,但角膜炎持续存在,重复角膜刮片和培养显示为弯孢霉菌属。用0.15%的局部两性霉素B和每日两次口服200毫克氟康唑治疗根除了感染,患者最终最佳矫正视力为20/20。

结论

弯孢霉菌属真菌可引起无痛性角膜炎。强化口服和局部抗真菌治疗成功根除了感染。

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