García-Romero D, Sanz-Robles H, Arrue I, Sánchez-Largo M E, Rodríguez-Peralto J L, Vanaclocha F
Servicio de Dermatología, Hospital Universitario 12 de Octubre, Ctra. de Andalucia km. 5,4. 28041 Madrid, Spain.
Actas Dermosifiliogr. 2006 Nov;97(9):599-602. doi: 10.1016/s0001-7310(06)73475-5.
Follicular keratosis may be a rare paraneoplastic disease having unknown etiopathogeny that is sometimes associated to myeloma whose diagnosis and evolution follow a parallel course. We describe the case of a 57-year-old female patient diagnosed of multiple myeloma 8 years ago. She developed generalized follicular hyperkeratotic spicules coinciding with leukemization of the myeloma.
毛囊角化病可能是一种病因不明的罕见副肿瘤性疾病,有时与骨髓瘤相关,其诊断和病程相互平行。我们描述了一名57岁女性患者的病例,该患者8年前被诊断为多发性骨髓瘤。她出现了全身性毛囊性角化过度性棘刺,与骨髓瘤的白血病化同时发生。