[一例伴有嗜酸性胸腔积液的弓蛔虫病]

[A case of toxocariasis with eosinophilic pleural effusion].

作者信息

Seki Masafumi, Hiromatsu Kenji, Kosai Kosuke, Fukuda Yuichi, Kakugawa Tomoyuki, Nakamura Fukumi, Izumikawa Koichi, Yanagihara Katsunori, Higashiyama Yasuhiko, Miyazaki Yoshitsugu, Hirakata Yoichi, Mukae Hiroshi, Tashiro Takayoshi, Kohno Shigeru

机构信息

Department of Internal Medicine, Kitakyushu City Yahata Hospital.

出版信息

Kansenshogaku Zasshi. 2006 Nov;80(6):716-20. doi: 10.11150/kansenshogakuzasshi1970.80.716.

DOI:10.11150/kansenshogakuzasshi1970.80.716

PMID:17176861

Abstract

A 76-year-old man admitted for general malaise with fever was found in clinical examination on admission to have eosinophilic pleural effusion, peripheral eosinophilia, and a slightly elevated inflammatory reaction. Immunological examination, including microplate ELISA, showed a high titer of specific antibody against Toxocara canis in both the serum and pleural effusion. We started treatment using albendazole, and found inflammatory findings and serum IgE were ameliorated. Parasitic disease is an important consideration in the differential diagnosis of eosinophilic pleural effusion, and serology is useful in screening for this.

摘要

一名因全身不适伴发热入院的76岁男性，入院时临床检查发现有嗜酸性胸腔积液、外周嗜酸性粒细胞增多以及炎症反应略有升高。包括微孔酶联免疫吸附测定（ELISA）在内的免疫学检查显示，血清和胸腔积液中抗犬弓首蛔虫特异性抗体滴度均很高。我们开始使用阿苯达唑进行治疗，发现炎症表现和血清免疫球蛋白E（IgE）有所改善。寄生虫病是嗜酸性胸腔积液鉴别诊断中的一个重要考虑因素，血清学检查对此筛查很有用。