具有自由基清除活性的多蕊蛇菰新酚类成分。

New phenolic constituents from Balanophora polyandra with radical-scavenging activity.

作者信息

Wang Kai-Jin, Zhang Ying-Jun, Yang Chong-Ren

机构信息

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, PR China.

出版信息

Chem Biodivers. 2006 Dec;3(12):1317-24. doi: 10.1002/cbdv.200690135.

DOI:10.1002/cbdv.200690135

PMID:17193246

Abstract

The 80% acetone extract of Balanophora polyandra Griff. (Balanophoraceae) was found to exhibit high radical-scavenging activity (SC(50)=14.48 mug/ml) towards 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals. Further chemical investigation led the isolation of two new hydrolysable tannins, balapolyphorins A (1) and B (2), together with 20 known phenolic compounds (3-22). Their structures were established by detailed spectroscopic analysis, and the radical-scavenging properties of all isolated compounds were determined by DPPH assay.

摘要

发现多蕊蛇菰（蛇菰科）的80%丙酮提取物对1,1-二苯基-2-苦基肼（DPPH）自由基具有高自由基清除活性（半数清除浓度SC(50)=14.48微克/毫升）。进一步的化学研究导致分离出两种新的可水解单宁，多蕊蛇菰素A（1）和B（2），以及20种已知的酚类化合物（3 - 22）。通过详细的光谱分析确定了它们的结构，并通过DPPH测定法测定了所有分离化合物的自由基清除特性。