Canger Emin Murat, Celenk Peruze, Alkan Alper, Günhan Omer
O.M.U. Faculty of Dentistry Department of Oral Diagnosis and Radiology, Samsun/Turkey.
Med Oral Patol Oral Cir Bucal. 2007 Jan 1;12(1):E7-9.
Plasma cell neoplasms (multiple myeloma, solitary plasmocytoma of bone and extra medullar plasmocytoma) are characterized by a monoclonal neoplastic proliferation of plasma cells. Solitary plasmocytoma of bone (SPB) is a localized form of them. SPB is most frequently seen in vertebrae and secondarily in long bones. Its presence in jaws is extremely rare and when it is seen, angulus and ramus mandible are most common sites of occurrence. Prognosis of SPB is worse than extra medullar plasmacytoma (EMP) and approximately 50% of SPB will transform to multiple myelom. A 76-year old woman consulted to our clinic with a chief complaint of slowly developed swelling in her mandible. She had an operation from caput femur because of plasmocytoma two months before. Panoramic radiography revealed a radiolucent lesion in the mandibular anterior region, 60x35 mm in dimension. Aspiration biopsy was performed and histopathological examination was reported as plasmocytoma. She was referred to the oncology department for treatment but died before the treatment finished.
浆细胞肿瘤(多发性骨髓瘤、骨孤立性浆细胞瘤和髓外浆细胞瘤)的特征是浆细胞的单克隆性肿瘤增殖。骨孤立性浆细胞瘤(SPB)是其中的一种局限性形式。SPB最常见于脊椎,其次是长骨。它在颌骨中极为罕见,一旦出现,下颌角和下颌支是最常见的发病部位。SPB的预后比髓外浆细胞瘤(EMP)差,约50%的SPB会转化为多发性骨髓瘤。一名76岁女性因下颌骨缓慢肿胀为主诉前来我院就诊。两个月前她因浆细胞瘤接受了股骨头手术。全景X线片显示下颌前部有一60×35mm大小的透射性病变。进行了穿刺活检,组织病理学检查报告为浆细胞瘤。她被转诊至肿瘤科进行治疗,但在治疗结束前死亡。