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[关于可能提高卵母细胞捐赠年龄限制的规定]

[Provisions for potentially raising the age limit for oocyte donation].

作者信息

van Kasteren Y M, Braat D D M

机构信息

Medisch Centrum Alkmaar, afd. Verloskunde en Gynaecologie, Wilhelminalaan 12, 1815 JD Alkmaar.

出版信息

Ned Tijdschr Geneeskd. 2006 Nov 25;150(47):2588-90.

Abstract

The introduction ofoocyte donation has provided a new perspective on reproduction for women with premature ovarian failure. In contrast to other forms ofassisted reproductive technology, the success ofoocyte donation is not affected by the age of the future mother. This has prompted a discussion on raising the age limit to allow older women to become pregnant. The health risk for the future mother is increased in older women compared with younger women but does not appear to be a sufficient reason to disqualify older women from undergoing the procedure. Lack of information regarding the effect of very late parenthood on the medical, psychological and social well-being of the future child poses the greatest concern. Should the age limit be extended for oocyte donation, treatment should be restricted to a research setting with a protocol for single-embryo transfer and extensive follow-up regarding the well-being of the future child.

摘要

卵母细胞捐赠的引入为卵巢早衰女性的生殖提供了新视角。与其他形式的辅助生殖技术不同,卵母细胞捐赠的成功率不受未来母亲年龄的影响。这引发了关于提高年龄限制以使老年女性能够怀孕的讨论。与年轻女性相比,老年女性作为未来母亲的健康风险增加,但这似乎并不是取消老年女性接受该程序资格的充分理由。关于高龄生育对未来孩子的医学、心理和社会福祉的影响缺乏相关信息,这引发了最大的担忧。如果要延长卵母细胞捐赠的年龄限制,治疗应仅限于研究环境,并采用单胚胎移植方案以及对未来孩子的福祉进行广泛随访。

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