Tümer Ali Riza, Dener Cenap
Department of Forensic Medicine, Hacettepe University School of Medicine, Ankara, Turkey.
J Forensic Sci. 2007 Jan;52(1):180-2. doi: 10.1111/j.1556-4029.2006.00316.x.
Sudden death due to acute pancreatitis has been rarely determined. A review of 3305 autopsies performed between 1991 and 2001 at the Council of Forensic Medicine found 12 cases (0.36%) with sudden death due to acute hemorrhagic pancreatitis without symptoms. A history of chronic alcohol ingestion was obtained from family in four cases (33%), and no stones were found in the bile ducts or in the gall bladders. During the autopsies, hemorrhage and edema were localized on the head of the pancreas in three cases and the whole pancreas in nine cases. The most common extrapancreatic pathology was found in the lung including pulmonary edema, alveolar hemorrhage, pleural effusion, and pulmonary congestion. There was no correlation between pulmonary and pancreatic damage. It is suggested that the forensic pathologists who are dealing with sudden unexpected death must not ignore the examination of pancreatic and extrapancreatic regions to avoid missing acute pancreatitis.
急性胰腺炎导致的猝死鲜有定论。对1991年至2001年间在法医委员会进行的3305例尸检进行回顾发现,有12例(0.36%)因无症状的急性出血性胰腺炎导致猝死。4例(33%)家属提供了长期饮酒史,胆管和胆囊均未发现结石。尸检过程中,3例胰腺头部出现出血和水肿,9例整个胰腺出现出血和水肿。最常见的胰腺外病理改变出现在肺部,包括肺水肿、肺泡出血、胸腔积液和肺充血。肺部和胰腺损伤之间无相关性。建议处理意外猝死的法医病理学家不要忽视胰腺和胰腺外区域的检查,以免漏诊急性胰腺炎。